Metronidazole is a powerful yet gentle ingredient that helps calm inflammation, reduce bacterial irritation, and support healing for hemorrhoids, anal fissures, and irritated perianal skin. In Bummed’s compounded creams, it works alongside targeted pain relievers and soothing agents to create a clean, comfortable environment that helps the body heal more effectively

Discover how diltiazem helps relieve hemorrhoid and anal fissure pain safely and effectively. Learn why this topical calcium channel blocker medication is ideal for long-term healing and is pregnancy-safe.

Nifedipine helps heal anal fissures and hemorrhoids by relaxing the anal sphincter and restoring blood flow. Learn how it powers Bummed’s Sensitive Care Rx Cream.

Learn how nitroglycerin works to relieve pain and promote healing for hemorrhoids and anal fissures. Discover why this powerhouse ingredient is central to advanced prescription creams for rapid, lasting comfort.

Meet bupivacaine—the long-lasting anesthetic behind real hemorrhoid and fissure relief. Learn how it works and where to find it in Bummed’s prescription creams.